产品货号:
Z12532
中文名称:
Caspase 5/CASP5抗体
英文名称:
Anti-Caspase 5/CASP5 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Caspase 5/CASP5 Antibody |
指标别名 | caspase 5;Caspase-5;ICE(rel)III;ICEREL-III;ICH-3;Caspase5;CASP5 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | CASP5 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Caspase-5 antibody was raised against a 14 amino acid synthetic peptide from the center of human Caspase-5.The immunogen is located within amino acids 170 - 220 of Caspase-5. |
计算分子量 | 50kDa |
成分 | Caspase-5 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | Caspase-5 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies.Unlike the apoptotic caspases,members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens.Members of this subfamily include caspase-1,-4,-5,and -12.Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1汕and IL-18.Caspase-5 can interact with caspase-1;both are constituents of the NALP1 inflammasome,a complex that can trigger the cleavage of pro-IL-1汕.Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma. |
Uniprot ID | P51878 |
基因名全称 | Caspase 5,apoptosis-related cysteine peptidase |
蛋白名全称 | Caspase 5,apoptosis-related cysteine peptidase |
推荐稀释比 | Casp-5 antibody can be used for the detection of caspase-5 by Western blot at 0.5 ~ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 2μg/mL.For immunofluorescence start at 2μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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